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A phenol peel is the deepest and most severe type of chemical peel available, using chemicals to remove the outer layers of skin. Wounding the skin cells has two effects: phenol peels can clear the way for a fresh layer of skin to grow back, and it can also stimulate collagen growth.

Phenol (also known as carbolic acid) may be used alone or modified by the addition of various ingredients, such as croton oil, water, olive oil, and septisol solution. These modified peels may have inventors names associated with them, like Stone Venner-Kellson, Baker-Gordon or Hetter formula.