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Xeomin uses botulinum toxin, as does Botox, to eliminate wrinkles by blocking neural signals and paralyzing the underlying muscles.

By Zeel Editorial Staff, Last updated: May 18, 2020

Regulatory approval: Approved by the FDA in July 2011.

Other names: incobotulinumtoxinA

Manufacturer: Merz Pharmaceuticals, LLC

Xeomin is the latest competitor to go up against Botox and Dysport. Though Xeomin has been thriving on the global market since 2005, the product was not introduced in the United States until 2010.

Like Botox and Dysport, Xeomin was initially approved for the treatment of blepharospasm and cervical dystonia, conditions that involve involuntary muscle spasms, to reduce abnormal head positioning, neck pain and eyelid spasms. The injectable wrinkle reducer is now approved for the treatment of moderate to severe glabellar lines—those "11's" that form between the eyebrows—though it will not be available until spring 2012.

Xeomin contains a form of botulinum toxin known as incobotulinumtoxinA, which varies slightly from the chemical composition of Botox and Dysport. When injected into the underlying muscle, Xeomin blocks the release of a wrinkle-causing chemical called acetylcholine. While Xeomin doesn't prevent all facial muscles from contracting, it does decrease the force with which the targeted muscles contract when you scowl, sneeze or otherwise contort your face.

What It's Good For

Xeomin is said to be a powerful treatment for glabellar lines, known as the vertical wrinkles or "11's" between the eyebrows. Xeomin injections effectively reduce the appearance of "dynamic" wrinkles—those that become evident when you frown, squint and laugh.

Who it works for: If you're worried about your frown lines, then stop! Scowling can actually exacerbate these wrinkles. If you're looking for a way to temporarily eliminate these lines, then Xeomin might just be it. The injectable wrinkle reducer can keep these creases at bay for up to four months.

Recommended age range: Xeomin is recommended in patients over the age of 18 and under 65.

When will I see results?: Initial studies have found that it takes approximately seven days to notice improvement after treatment with Xeomin. As with any injection, your muscles may become swollen or bruised afterward depending on your individual reaction.

How long it lasts: Xeomin injections last an average of 12 weeks, according to clinical studies, though the product is still in trial stages in the US. Patients should wait at least 12 weeks before re-injecting an area with Xeomin.

Key benefits of Xeomin: Because of its chemical construction, Xeomin is said to be more “pure” than Botox and Dysport, meaning that allergic reaction is less likely. In addition, Xeomin does not have to refrigerated, and it has a longer shelf-life than its predecessors. With simpler storage requirements, Xeomin may be potentially cheaper once it hits the market—a bonus for your wallet.

Licensed uses: Xeomin was approved by the FDA in July 2011 for the treatment of glabellar lines. It has already gained clearance in 14 countries (and counting) around the world, including the United Kingdom, France and Spain.

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