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Perlane is a long-lasting hyaluronic acid-based filler effective for deep lines and wrinkles.

Before You Go

Questions to ask your doctor:

  • Is Perlane the best injectable for my wrinkles?
  • How deeply do you plan to inject the Perlane?

Pre-procedure prep for Perlane: If requested, a topical anesthetic can be applied 20 minutes before the Perlane injection, though the lidocaine version of Perlane may make this unnecessary.

On the day of treatment: Avoid medication that can increase bruising or bleeding, like Advil and Motrin.

What To Expect

Immediately afterwards, you may notice bruising, redness, swelling, tenderness, aches, and itching. Speak to your practitioner if your skin looks bluish.

Who should do it: Perlane can be injected by a cosmetic surgeon or dermatologist. In some states, nurse practitioners may also legally provide treatment if supervised by a doctor. In any case, make sure that Perlane is injected by board certified, trained (and skilled!) hands as proper placement of the injections is vital.

Duration: Expect the entire process to take about an hour.

How Painful Is It?

Perlane injections are said to be mildly to moderately uncomfortable.

Options for anesthesia: Some Perlane is mixed with lidocaine, a painkiller. You can also request an anesthetic cream or, if you are extremely sensitive, a nerve blocker. (Keep in mind, however, that the injection of the nerve blocker is painful in of itself.)

Find experts who offer Perlane near you