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Juvederm is one of the most popular hyaluronic-acid based facial fillers.

By Zeel Editorial Staff, Last updated: May 18, 2020

Treatment Basics

Regulatory approval: Approved by the FDA in June 2006.

Other names: Juvederm, Juvederm Ultra, Juvederm Ultra Plus, Juvederm XC Ultra, Juvederm XC Ultra Plus

Manufacturer: Allergan, Inc.

Juvederm is one of the most popular facial fillers. It's largely composed of hyaluronic acid, a substance that occurs naturally in the skin. Juvederm is available in two different strengths: Ultra and Ultra Plus. While both fillers have the same amount of hyaluronic acid, Juvederm Ultra Plus has a higher degree of cross-linking, making it thicker and a little firmer.

What It's Good For

Juvederm can be injected into the face and lips, and is often used to treat nasolabial folds. Juvederm Ultra is designed to smooth shallow lines, while Juvederm Ultra Plus is thick enough for deeper wrinkles and facial folds. Both are available with lidocaine added to decrease discomfort.

Who it works for: Juevederm is a good all-around filler with an excellent safety record. Like other hyaluronic acid fillers, Juvederm carries little to no risk of permanent hyperpigmentation, or skin discoloration, for individuals with darker skin.

Recommended age range: Juvederm should not be used before your 18th birthday.

When will I see results?: You will see the results of your Juvederm injections immediately, though the treated area may appear swollen or bruised for a few days.

How long it lasts: Average Juvederm injections last between six and 12 months. The difference between Juvederm Ultra and Ultra Plus is in how long the injectables last in the body before being reabsorbed. Ultra Plus is more durable than Ultra due to a higher level of "crosslinking" between molecules. Ultra Plus lasts up to 12 months in the body while Ultra lasts up to nine.

Key benefits of Juvederm: Juvederm is a great all-around filler. It's long-lasting and has a moderately thick consistency, making it suitable for use almost anywhere on the face or body.

Licensed uses: Juvederm injectable gel (including Juvederm Ultra, Juvederm Ultra Plus, Juvederm Ultra XC, and Juvederm Ultra Plus XC), can smooth moderate to severe facial wrinkles and folds, including nasolabial folds.

Did you know?: Juvederm is the number one selling facial filling procedure in the United States.

Recommended Uses
Name Description Cost
Acne scars Juvederm Ultra Plus is approved for filling in superficial skin depressions. This thick filler treats deep valley acne scars for about $450 to $900 - the cost of a single syringe. Smaller...more The amount of Juvederm you require to fill acne scars depends on how many scars you have and...more
Crow's feet Juvederm is used as a filler, normally in conjunction with a muscle relaxant like Botox or Dysport, to fill in and smooth crow’s feet just below the surface. Juvederm Ultra costs between...more A single syringe of Juvederm can typically fill most deep, static crow’s feet wrinkles. ...more
Dark circles under eyes Juvederm is made of hyaluronic acid, a sugar-based gel found naturally in human skin. All HA fillers tend to attract water, which can give a natural appearance to the injected area. ...more The dark circles under the eye, which are typically caused by the thinning of the fat pads...more
Downturned mouth A thinning of the lower lip can caused a downturned mouth, and Juvederm works by temporarily enlarging the lower lip. To treat a downturned mouth, Juvederm is injected into the edge of the...more Plumping a downturned mouth into a cheerier expression should not take more than one syringe...more
Glabellar lines (frown lines) Juvederm, a hyaluronic acid-based filler, is a good second-line treatment for glabellar lines. It’s not appropriate as the only treatment for these deep, motion-caused wrinkles, but it is...more Juvederm is sometimes used to fill particularly deep and static glabellar wrinkles. Opt for...more
Horizontal forehead wrinkles If forehead wrinkles are especially deep and static, then they can be leveled off with a filler like Juvederm Ultra. Juvederm Ultra costs between $400 and $800 per syringe. It lasts about...more A full syringe of Juvederm Ultra can be used to treat very deep and static forehead...more
Lip wrinkles ("smoker's mouth" or "lipstick lines") One syringe of Juvederm will smooth out lipstick lines. Juvederm can also be used to enhance the upper vermilion border of the lip (a technique called the “Paris Lip”) which both...more Opt for Juvederm Ultra, not Ultra Plus, in this relatively thin-skinned area. One syringe...more
Marionette Lines Juvederm is a hyaluronic acid (HA) filler and a good treatment for marionette lines. Hyaluronic acid naturally occurs in the skin, meaning Juvederm does not cause allergic reactions. The...more Price ranges from $400 to $900 for one syringe.
Nasolabial folds (smile lines) Juvederm, a hyaluronic acid filler, is one of the most popular fillers for nasolabial folds. Some doctors say Juvederm attracts a bit more water than Restylane, meaning it may expand more in...more One syringe of Juvederm Ultra Plus, at a minimum, is used to fill the nasolabial folds. ...more
Thinning lips On average, an injection of Juvederm will last six to nine months. Juvederm is made of hyaluronic acid, a substance found naturally in human skin. There is no risk of rejection. All HA...more One syringeful will cost between $400 and $800, and one syringe is usually all that is...more
Wrinkles Juvederm is available in two strengths: Ultra and Ultra Plus. Juvederm Ultra Plus is thicker and better suited for deep, defined nasolabial folds, marionette lines, and forehead lines. It...more Wrinkle treatment with Juvederm depends on the type and severity of wrinkles as well as the...more

Who's Done It?

In 2008 Golden Globe nominee Virginia Madsen decided to fill in the creases surrounding her mouth with Juvederm. Madsen raved to People that not only was she satisfied with Juvederm, but her family and peers were equally as thrilled. "They were surprised that I looked so 'normal,'" Madsen explained.

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