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Nasolabial Folds (smile Lines)

Fillers For Nasolabial Folds
Name Description Cost
ArteFill The nasolabial folds are one of the primary targets for treatment by Artefill. Artefill can last five years or more and is classified as a permanent filler. Artefill consists of tiny plastic...more Depending on the depth of the nasolabial folds, up to three syringes of Artefill may be...more
Fat transfer (injection) Fat transfers are a good and long-lived method for filling nasolabial folds. The results tend to be long-lasting – but they are unpredictable. Some patients see their fat transfers...more Fat transfers cost about $1,500 or more per treatment.
Juvederm Juvederm, a hyaluronic acid filler, is one of the most popular fillers for nasolabial folds. Some doctors say Juvederm attracts a bit more water than Restylane, meaning it may expand more in...more One syringe of Juvederm Ultra Plus, at a minimum, is used to fill the nasolabial folds. ...more
Perlane Perlane is an effective treatment for moderately deep - or very deep – nasolabial folds, because it has slightly larger molecules than other hyaluronic acid fillers. It is available in a...more Perlane costs between $500 and $800 for a 1cc syringe and is available with added lidocaine....more
Radiesse Radiesse is a firm and durable filler made of tiny calcium spheres suspended in a sugar-based gel. This creates a dual action - the spheres and gel fill up the fissures of the nasolabial...more Radiesse is perhaps one of the best solutions for long-lasting plumping of the nasolabial...more
Restylane Nasolabial folds are perfectly suited to treatment with Restylane. Restylane is a good all-arounder in the world of fillers. It is a “soft” filler that will not cause a hard, stretched...more One to two syringes of Restylane will be required, costing between $800 and $1,600 (for two...more
Sculptra Sculptra is a good option for filling the nasolabial folds when the face has very little fat or there is significant volume loss. Scultpra is a semi-permanent filler composed of the powdered...more The cost of Sculptra depends on how many vials are needed to fill the nasolabial folds. ...more

Treatments Not Recommended
Name Description
Silikon 1000 The nasolabial fold area is constantly mobile, as we smile, chew and so forth. This increases the risk that Silikon 1000 will migrate. As it’s a permanent (silicone) filler, use of Silikon 1000 in the nasolabial folds is not recommended.
Botox Botox should not be used to treat nasolabial folds. There is a significant danger of temporary weakening of the muscles that govern speech or other important functions.
Dysport Dysport should not be used to treat nasolabial folds. As it works by weakening muscles, there is a risk that muscles that govern speech and other important functions will be affected.

Treatment options: One of the most common methods of reducing the appearance of nasolabial folds is the use of injectables. Radiesse, Perlane, Juvederm, Restylane, Sculptra and Artefill are all popular with dermatologists and surgeons seeking to reduce the appearance of these mouth-bracketing wrinkles.

Fillers work in two distinct ways. Perlane, Juvederm and Restylane manually fill wrinkles with hyaluronic gel, a water-attracting acid naturally found in the skin. Radiesse, Artefill and Sculptra work by stimulating collagen production deep beneath the skin's surface. The extra collagen plumps the skin, thus filling in wrinkles from the bottom up.

There are some other types of fillers as well. One option is fat injection, which using the patient's own fat reserves to fill in the nasolabial folds. Fat injections last a widely varying amount of time, from a few weeks to over a year, depending on how much fat is used and on the patient's genetic background.

Some doctors use silicone oil off-label, as a sort of permanent collagen attractor. When it works, it's great - but remember that when fillers are permanent, so are any problems they cause.

Surgical treatments: Several varieties of face lifts, such as the midface lift, can improve nasolabial folds. For very mature patients, a nasolabial fold excision - essentially punching out the fold surgically - may be performed, though this surgery causes facial scarring and is typically only performed if other measures fail.