A hyaluronic acid dermal filler, Perlane has larger molecules than other HA fillers like Restylane and Juvederm, which makes it especially well-suited to very deep facial wrinkles and folds. Hyaluronic acid is a naturally occurring compound found in human skin, so most people are not allergic to it.
Perlane is manufactured by Medicis, the same company that makes Restylane; Perlane is designed to be injected deeper into the skin than Restylane.
What It's Good For
Perlane addresses facial wrinkles, fine lines, nasolabial folds, and sunken cheeks. The HA filler can enhance your lips by adding definition to the border. Perlane may also soften acne scars.
Who it works for: Whereas Restylane is often used for finer lines and thinner skin, Perlane is effective for deeper lines and wrinkles. It can also plump larger areas of skin and last up to three times as long.
Recommended age range: Perlane (and all hyaluronic acid fillers) shouldn't be used by people under the age of 18.
When will I see results?: Perlane is a filler, so you'll see some results immediately. Because Perlane is injected into deeper layers of skin, it increases collagen production as well. Because increased collagen causes additional plumping, the final results of Perlane injections may take up to six months.
How long it lasts: Perlane breaks down most quickly in the lips - you will need touchups every four to six months. Elsewhere in the face, Perlane lasts for up to nine months.
Key benefits of Perlane: You don't need to be tested for allergies before Perlane injections. It's the best hyaluronic filler if you need substantial filling power. If Perlane is misplaced or becomes lumpy, it can be safely dissolved with an injection of hyaluronase.
Licensed uses: Perlane was approved in May 2007 as a gel implant to add volume to facial tissues. It can smooth wrinkles and folds around the nose and mouth. Your nasolabial folds may thank you.